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doi: 10.1038/nature23475 140 SwamyMPathakSGrzesKMDamerowSSinclairLVVan AaltenDMFet al

Mild injection-site reactions affect approximately 5-10 percent of recipients, while systemic effects are less frequent but warrant careful monitoring

This comes from the fact that, the virus hijacks the host cell transcriptional/translational machinery during acute infection to produce large amounts of viral proteins and RNA, while shutting down host messenger RNA translation (121)

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